AMES, Iowa (AP) - Angie Welle scored 18 points on 7-for-8 shooting and No. 5 Iowa State pulled away early in the second half to beat San Francisco 87-60 on Sunday.

Iowa State (8-0) could not shake San Francisco (3-4) in the first half despite shooting 60 percent and outrebounding the Lady Dons 22-16. But a 28-4 run in the first 10:20 of the second half settled the outcome and Iowa State coach Bill Fennelly soon began pulling his starters.

Lindsey Wilson went 7-of-10 on field goals, mostly with driving layups, and scored 16 points for Iowa State, which won its 21st straight non-conference game. Tracy Gahan, 5-for-6 from the field, scored 14 points, Megan Taylor 11.

San Francisco entered the game shooting 42 percent from 3-point range and moved the ball well at times against Iowa State's 2-3 zone, but couldn't make their shots. The Lady Dons were just 7-of-28 from beyond the arc and shot only 32 percent overall.

Iowa State shot 59.6 percent and was 10-for-17 on 3-pointers.

Kim Whisler's 20 points led San Francisco, which lost for the fourth time in five games.

Iowa State led 44-33 at halftime, and San Francisco cut the lead to nine when Whisler scored the first basket of the second half. But the Lady Dons made only two shots over the next 9 1/2 minutes.

Wilson hit a 3-pointer and Welle had five points in a 10-0 run that got the Cyclones started. It was 57-39 when Iowa State ran off 15 straight points, including 3-pointers by Erica Junod and Erica Haugen and a three-point play by Welle, who's shooting 70.5 percent for the season.

Wilson converted a three-point play off a layup to give Iowa State its biggest lead, 75-41 with 8:47 left.

Whisler scored San Francisco's first three baskets of the second half. No other San Francisco player scored in the half until Melanie Turner hit a jump shot from the baseline with 9:13 left.